The Src family kinase Hck regulates mast cell activation by suppressing an inhibitory Src family kinase Lyn
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منابع مشابه
The Src family kinase Hck regulates mast cell activation by suppressing an inhibitory Src family kinase Lyn.
IgE/antigen-dependent mast cell activation plays a central role in immediate hypersensitivity and other allergic reactions. The Src family tyrosine kinase (SFK) Lyn is activated by the cross-linking of high-affinity IgE receptors (FcepsilonRI). Activated Lyn phosphorylates the FcepsilonRI subunits, beta and gamma, leading to subsequent activation of various signaling pathways. Lyn also plays a ...
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ژورنال
عنوان ژورنال: Blood
سال: 2007
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood-2007-01-066092